??????????? ??? ?? ???,
???? ???? ???-???? ?? ?? ??
[??] ??? ??, ??? ???(????)
??? ???? ?? ???? ???? ?????? ? ???? ??? ?? ???? ?? ??? ?? ???? ???, ?? ???? ??? ??? ????(scaffold)? ?? ??? ??? ??? ?? ?? ????? ??? ?? ??.
* ???? : ??? ??? ??? ? ?? ?? ??? ???? ??? ??? ??? ??? ?? ‘?? ?’? ?? ???? ???.
?? ??????(?? ???) ??????????? ??? ?? ???(?1?? ??? ???)? ??? ??? ??? ?? ??? ??? ??? ??? ?? ??? ?????? ??????, ?? ? ?? ???? ???? ?????(shape memory hydrogel; SMH) ??? ??? ?? ????.
?? ??? ?? ??? SMH(Cryo-gel)? ?? ?? ?? ??? ?? ????, ??? ??? ???? ???? ??? ??? ???? ??? ?? ?? ?????? ??? ??? ???. ?? ??? ???? ?? ??? SMH(F-gel)? ??, ????? ??? ??? ?????? ?? ???? ??? ?? ?? ?? ??? ?????.
* ?? ???? ??? ??? ???/????/?? ??? ?? ??? ?? ?? ???? ??? ?? ??? ???? ? ????? ??? ??? ?? ?? ?? ?·??? ???? ???? ????.
???? ??? ??? ???? ?? ???, ? ?? SMH? ??? ??? ?? ?????? ???? ?? ??? ??????, ??? ???? ?? ?????(shape memorable biocomposite hydrogel)? Cryo-gel? ?? ?? ???? ??? ? ???, ?? ?? F-gel? ?? ?? ???? ???? ??, Cryo-gel ?? ??? ?? ???? ??? ?? ????.
??? ??? ???? ?? ?????? ???? ? ???? ?? ?????? ?? ??? ???? ???(heparin) ?? ?? ???? ?? ????? ??????(hydroxyapatite)? ??? ???? ????. ???? ?? ?? ??? ???? ??????, ??? ????? ?? ?? ???? ??? ?? ????.
?? ?? ??? 3D ??? ??? ??? 3?? ??? ??? ???? ????, ??? 3?? ???? ????? ??? ? ???? ? ?? ???? ???? ?? ???, ???? ??(minimally invasive operation)? ?? ??? ???? ????(injectable scaffold)?? ?? ??? ?? ????.
??? ??? “?? ?? ??? ??? ??? ?? ???? ?? ?? ? ???? ???? ????, ?? ??? ??? ???????? ?? ??? ?? ??? ??? ??? ??”? ????.
????? ??? ?? ???? ?????? ??? ??? ??-?? ?? ?? ?? ??(myotendinous junction)(?1?? ??? ???) ? ???? ????? ??? ???/?????? ??? ???(?1?? ??? ???)? ???, ??? ??? ??? 3?? ??-???? ?? ??? ????-???? ??? ? ??? ????.
?? ?? ??? ?????? ????????????? ???? ??????, ?? ??? ?? ?????? ????? ??? ??(Applied Physics Reviews, IF = 19.2, 22? 6?)? feature article? ??????, ??? ?? ?????? ???????? & ??????? ???(Bioengineering & Translational Medicine, IF = 10.7, 22? 3, 4?)? ?? ?????.
※ ???
- Collagen-based shape-memory biocomposites (Applied Physics Reviews)
- A bioprinted complex tissue model for myotendinous junctionwith biochemical and biophysical cues (Bioengineering & Translational Medicine)
- Bioprinted hASC-laden collagen/HA constructs with meringue-like macro/micropores (Bioengineering & Translational Medicine)
※ Feature article ?? ??:
??
