??? ??? ?? ???, ???????? ??? ??? ??
- Peroxidase ???? ???? ???? ?? Chemodynamic ??? ??
¡ø (????) ??? ??? ??, Thien ?????(?1??), Nguyen ?????(???), ??? ?????(???)
??? ??? ?? ???(?1?? Thien ?????)? 'Peroxidase ???? ????(upconversion) ???? ?? Chemodynamic ???'? ??? ???????(TNBC) ??? ??? ???? ????.
???????? ??? ? ?? ???? ??? ?? ???? ??? ??? ???? ?????. ?? ? ??? ??? ?????? Fenton reaction-driven Chemodynamic Therapy? ???? ??. ? ???? ?? ????(TME)? ??? ??? ???? H2O2? ??? ???? ????? ????. ?? ?? ?? ???? ???? ?? ????? ???? ???? ???? ???, ?? ??? ??? ? ?? ?? ??? Fe2+ ?? Fe3+? ????. ??, TME?? pH? ??? 2~4? ??? ??? ????? ???? ???.
???? ?? ??? ?? ??? ?????? ???? ??? ??? ?? ???? ????? ??? ?? -OH? ??? ? ?? ????? ?? ?? ?? ??? ????.
? ????? Fe ??? UV ?? ??? g-C3N4(graphitic carbon nitride) ????? ???? ???? UV ??? ??? ??? ? ??? ???? ??(UmFe)? ???? ??? ????? ??? UmFe-OA@hPM? ???? ??? ????. ??? ??? ???? ????? ??? ?? ???? ?????, UmFe-OA@hPM? ?? ? ???? ???? ????? ??? Fenton ??? ?? ???? ????(chemodynamic) ??? ???? ??.
??? ??? Fenton ??? 808nm ???? ??? ?? ??? ??? ???? ? ??. ?? UmFe ???? ??? ?????(OA)? ?? ? ?? ?????? ??? ?????? ??? ???? ??? ACSL4(Acyl-CoA synthetase long-chain family member 4)? ?? ??? ??? ??? ???? ?? Fenton ??? ??? ????.
UmFe-OA@hPM ?? ???? ???? ??? ??? ??? ???? ferroptosis? ????, ?? ?? ??? ??? ???? ??? ??? ??? ?? ?? ??? ???. ??, ???? ????? ?? ????? ?? ?? ??? ??? ??? Chemodynamic /Immunotherapy ????? ????. ?? ??????? ??? ??? ???? ??? ? ?? ??? ????.
??? ??? ?? ?? ??? ??????? ????????? ? ??????????(MRC) ???? ?????, ?? ? ?? ??? ??? ???? ????? ??? ?????(Advanced Functional Materials, IF: 19.0, JCR ranking 4.4%) 2024? 5??? ????.
¡ù ???: Peroxidase-Mimicking Iron-Based Single-Atom Upconversion Photocatalyst for Enhancing Chemodynamic Therapy
¡ù ????:
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